Kihadanin B (73793-68-7)可以通过抑制 3T3-L1 脂肪细胞中的 Akt-FOXO1-PPARγ 轴来减少脂质积累,从而抑制脂肪生成。Kihadanin B can repress the adipogenesis by decreasing lipid accumulation through the suppression of the Akt-FOXO1-PPARγ axis in 3T3-L1 adipocytes.
| 中文别名 | Kihadanin B,基哈达宁B(,MSDS,熔点,溶解度) |
| 英文别名 | Kihadanin B;(1R,2R,4S,7R,8S,11R,12R,18R)-7-(2-hydroxy-5-oxo-2H-furan-4-yl)-1,8,12,17,17-pentamethyl-3,6,16-trioxapentacyclo[9.9.0.02,4.02,8.012,18]icos-13-ene-5,15,20-trione |
| CAS号 | 73793-68-7 |
| SMILES | CC1(C2CC(=O)C3(C(C2(C=CC(=O)O1)C)CCC4(C35C(O5)C(=O)OC4C6=CC(OC6=O)O)C)C)C |
| Inchi | InChI=1S/C26H30O9/c1-22(2)14-11-15(27)25(5)13(23(14,3)8-7-16(28)34-22)6-9-24(4)18(12-10-17(29)32-20(12)30)33-21(31)19-26(24,25)35-19/h7-8,10,13-14,17-19,29H,6,9,11H2,1-5H3/t13-,14+,17?,18+,19-,23-,24+,25+,26-/m1/s1 |
| InchiKey | LUSHRJRLUBDDTB-KNQGVANASA-N |
| 分子式 Formula | C26H30O9 |
| 分子量 Molecular Weight | 486.5g/mol |
| 闪点 FP | 252.8±26.4 ℃ |
| 沸点 Boiling point | 740.9±60.0 ℃ at 760 mmHg |
| 密度 Density | 1.4±0.1 g/cm3 |
| 蒸汽压 Vapor Pressure | 0.0±5.5 mmHg at 25℃ |
| 性状 | Solid power |
| 储藏条件 Storage conditions | 4℃条件下存储,-4℃条件下存储更佳 |