UNC4203 is a potent and selective MERTK Inhibitor. UNC4203 showed IC50 MerTK=2.4 nM (Ki=0.42 nM); IC50 Axl = 80 nM (Ki=40.22 nM); IC50 Tyro3 = 9.1 nM (Ki=3.87 nM). IC50 FLT3 = 39 nM *Ki=16.14 nM). T1/2 = 3.0 h; %F=15. UNC4203 may be a potential candidate for cancer treatment. References:
纯度:≥98%
CAS:1818234-19-3