PNU109291 is a potent and selective 5-HT1D receptor agonist that exhibits > 600-fold selectivity over 5-HT1A and 5-HT2A receptors. PNU109291 reduces dural plasma extravasation evoked by trigeminal ganglion stimulation. References: Watts SW, Darios ES, Seitz BM, Thompson JM. 5-HT is a potent relaxant in rat superior mesenteric veins. Pharmacol Res Perspect. 2015 Feb;3(1):e00103. doi: 10.1002/prp2.103. Epub 2015 Jan 5. PubMed PMID: 25692021; PubMed Central PMCID: PMC4317234.

纯度：≥98%

CAS：187665-60-7