Ranitidine (also known as AH19065) is a potent histamine H2-receptor antagonist with IC50 of 3.3 ± 1.4 uM. It is used to treat stomach or intestinal ulcers by inhibiting stomach acid production. Ranitidine HCl sensitizes hepatocytes to killing by cytotoxic products from activated neutrophils, whereas Famotidine lacks this ability. Ranitidine inhibits the production of tumor necrosis factor-alpha (TNF-alpha) in monocytes stimulated with lipopolysaccharide in vitro.
纯度:≥98%
CAS:66357-35-5