CAS NO: | 1984862-48-7 |
规格: | ≥98% |
OABK is a small molecule switch that can be used to control protein activity. Genetic encoding of OABK using a pyrrolysyl tRNA synthetase/tRNACUA pair in mammalian cells enables the site-specific introduction of a small molecule-removable protecting group into the protein of interest. A phosphine-mediated Staudinger reduction is used to re-activate protein function. References: Small Molecule Control of Protein Function through Staudinger Reduction Ji Luo, Qingyang Liu, Kunihiko Morihiro, Alexander Deiters Nat Chem. Author manuscript; available in PMC 2017 Jan 25.Published in final edited form as: Nat Chem. 2016 Nov; 8(11): 1027–1034. Published online 2016 Jul 25. doi: 10.1038/nchem.2573 PMCID: PMC5119652
纯度:≥98%
CAS:1984862-48-7
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