O(6)-Benzylguanine is an MGMT inhibitor that prevents the repair of DNA damage induced by chemotherapeutics. It allows apoptosis and other mechanisms of cell death to occur. References: Sun G, Zhao L, Fan T, Li S, Zhong R. Investigations on the effect of O(6)-benzylguanine on the formation of dG-dC interstrand cross-links induced by chloroethylnitrosoureas in human glioma cells using stable isotope dilution high-performance liquid chromatography electrospray ionization tandem mass spectrometry. Chem Res Toxicol. 2014 Jul 21;27(7):1253-62. doi: 10.1021/tx500143b. Epub 2014 Jun 17. PubMed PMID: 24914620.

纯度：≥98%

CAS：19916-73-5