CAS NO: | 518-28-5 |
规格: | ≥98% |
Podofilox, formerly known as Podophyllotoxin, is a potent inhibitor of microtubule assembly and DNA topoisomerase II. It is a kind of non-alkaloid toxin lignan found in the roots and rhizomes of Podophyllum plant and has shown to inhibit the growth of various carcinoma cells. Podophyllotoxin is a natural product that inhibits the polymerization of tubulin and has served as a prototype for the development of diverse antitumor agents in clinical use. References: Tyring S, Edwards L, Cherry LK, Ramsdell WM, Kotner S, Greenberg MD, Vance JC, Barnum G, Dromgoole SH, Killey FP, Toter T. Safety and efficacy of 0.5% podofilox gel in the treatment of anogenital warts. Arch Dermatol. 1998 Jan;134(1):33-8. PubMed PMID: 9449907.
纯度:≥98%
CAS:518-28-5
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