Atecegatran is a thrombin inhibitor. Atecegatran is an active metabolite of atecegatran metoxil ( atecegatran fexenetil and AZD0837). AZD0837 is an orally bioavailable direct thrombin inhibitor under development for the prevention of stroke and systemic embolism in patients with non-valvular atrial fibrillation. References: Lip GY, Rasmussen LH, Olsson SB, Jensen E, Hamrén B, Eriksson UG, Wahlander K. Exposure-response for biomarkers of anticoagulant effects by the oral direct thrombin inhibitor AZD0837 in patients with atrial fibrillation. Br J Clin Pharmacol. 2015 Dec;80(6):1362-73. doi: 10.1111/bcp.12719. Epub 2015 Sep 22. PubMed PMID: 26174611.
纯度:≥98%
CAS:917904-13-3