NA 0345 is a SF 2370 analogue that produces a selective inhibition of the alpha 1-mediated PIE, probably through inhibition of the alpha 1-adrenoceptor-mediated activation of PKC. References: Endoh M, Norota I, Takanashi M, Kasai H. Inotropic effects of staurosporine, NA 0345 and H-7, protein kinase C inhibitors, on rabbit ventricular myocardium: selective inhibition of the positive inotropic effect mediated by alpha 1-adrenoceptors. Jpn J Pharmacol. 1993 Sep;63(1):17-26. PubMed PMID: 8271527.
纯度:≥98%
CAS:120925-60-2