DDX3-IN-1 (Compound 16f) 是 DEAD-box 多肽 3 (DDX3) 抑制剂。DDX3-IN-1 具有抗病毒活性,对 HIV 和 HCV 的 CC50 分别为 50 和 36 μM。
CAS:1919828-83-3
分子式:C17H17N5O
分子量:307.35
纯度:98%
存储:Store at -20°C
Background:
DDX3-IN-1 (Compound 16f) is a DEAD-box polypeptide 3 (DDX3) inhibitor with CC50s of 50 and 36 μM for HIV and HCV, respectively. Antiviral activity[1].
[1]. Brai A, et al. Human DDX3 protein is a valuable target to develop broad spectrum antiviral agents. Proc Natl Acad Sci U S A. 2016 May 10;113(19):5388-93.