DDRInhibitor是一种高效的盘状结构域受体(discoidindomainreceptor)抑制剂,对DDR2的IC50值为3.3nM,在浓度为1.5nM时,对DDR1有53%的抑制作用。
CAS:1644069-80-6
分子式:C23H20FN5O2
分子量:417.44
纯度:98%
存储:Store at -20°C
Background:
DDR Inhibitor is a potent discoidin domain receptor (DDR) inhibitor, with an IC50 of 3.3 nM for DDR2, and shows 53% inhibition on DDR1 at 1.5 nM.
DDR Inhibitor (Example 6) is a potent DDR inhibitor, with an IC50 of 3.3 nM for DDR2, and shows 53% inhibition on DDR1 at 1.5 nM[1].
[1]. Gordon Saxty, et al. Imidazo-condensed bicycles as inhibitors of discoidin domain receptors (ddrs)