L-Quebrachitol 是从多种植物中分离得到的天然产物,通过上调 BMP-2、runt 相关转录因子 (Runx2)、MAPK (ERK, JNK, p38α) 和 Wnt/β-catenin 信号通路来促进成骨细胞生成。
CAS:642-38-6
分子式:C7H14O6
分子量:194.18
纯度:98%
存储:Store at -20°C
Background:
L-Quebrachitol is a natural product isolated from many plants, promotes osteoblastogenesis by uppregulation of BMP-2, runt-related transcription factor-2 (Runx2), MAPK (ERK, JNK, p38α), and Wnt/β-catenin signaling pathway[1].
[1]. Yodthong T, et al. l-Quebrachitol Promotes the Proliferation, Differentiation, and Mineralization of MC3T3-E1 Cells: Involvement of the BMP-2/Runx2/MAPK/Wnt/β-Catenin Signaling Pathway. Molecules. 2018 Nov 26;23(12).