activator of ClC-2 chloride channels
CAS:136790-76-6
分子式:C20H32F2O5
分子量:390.46
纯度:98%
存储:Store at -20°C
Background:
Lubiprostone(SPI-0211;RU0211) is a gastrointestinal agent used for the treatment of idiopathic chronic constipation.Target: OthersLubiprostone is a bicyclic fatty acid derived from prostaglandin E1 that acts by specifically activating ClC-2 chloride channels on the apical aspect of gastrointestinal epithelial cells, producing a chloride-rich fluid secretion. These secretions soften the stool, increase motility, and promote spontaneous bowel movements (SBM). From Wikipedia.
参考文献:
[1]. http://en.wikipedia.org/wiki/Lubiprostone