Empesertib(BAY1161909)是一种有效的Mps1抑制剂,IC50值<1nM。
CAS:1443763-60-7
分子式:C29H26FN5O4S
分子量:559.61
纯度:98%
存储:Store at -20°C
Background:
Empesertib (BAY 1161909) is a potent Mps1 inhibitor, with an IC50 of< 1 nM.
BAY 1161909 is a potent Mps1 inhibitor, with an IC50 of< 1 nM. BAY 1161909 also shows anti-tumor effect, suppressing the proliferation of Hela cells, with an IC50 of< 400 nM[1].
[1]. SCHULZE, Volker, et al. PRODRUG DERIVATIVES OF SUBSTITUTED TRIAZOLOPYRIDINES. WO2014198647A2