ML230(CID44640177;SID88095709)是一种ATP结合转运因亚型ABCG2的选择性抑制剂，对ABCG2的抑制作用是ABCB1的36倍，EC50值分别为0.13μM和4.65μM。
CAS：1776055-05-0
分子式：C25H21N5O3
分子量：439.47
纯度：98%
存储：Store at -20°C

Background:

ML230 (CID44640177; SID 88095709) is a selective inhibitor of ATP-binding cassette (ABC) transporter ABCG2, and 36-fold selective for ABCG2 over ABCB1 with EC50s values of 0.13 μM and 4.65 μM, respectively[1]. EC50: ABCG2 (0.13 μM)[1]

[1]. Strouse JJ, et al. Selective Efflux Inhibition of ATP-binding Cassette Sub-family G Member 2. Probe Reports from the NIH Molecular Libraries Program. November 30, 2010.