Pulchellin is a type-2 Ribosome Inactivating Protein (RIP), whose action mechanism proposed would be initiate by B-chain binding on glycoconjugate onto the cell surface (lectinic chain). pulchellin isoforms toxicity is the interaction between B-chain lectinic and the glycosyl residues on cell surface. pulchellin A chain is a novel of selective immunotoxin cytotoxicity. References: Huang H, Niu J, Wang F, Hu L, Yu Q. A natural compound derivative P-13 inhibits STAT3 signaling by covalently inhibiting Janus kinase 2. Invest New Drugs. 2018 Aug 3. doi: 10.1007/s10637-018-0637-2. [Epub ahead of print] PubMed PMID: 30073465.
纯度:≥98%
CAS:6754-35-4