Sultiame是一种carbonicanhydrase抑制剂,广泛用作抗癫痫药。
CAS:61-56-3
分子式:C10H14N2O4S2
分子量:290.36
纯度:98%
存储:Store at -20°C
Background:
Sultiame is a carbonic anhydrase inhibitor, widely used as an antiepileptic drug.
Sultiame (Sulthiame) is a sulphonamide, and it may exerts antiepileptic activity by producing a modest intracellular acidosis in central neurons via acting as a carbonic anhydrase inhibitor, thereby reducing the frequency of action potentials and epileptiform bursts[1].
[1]. Milburn-McNulty P, et al. Sulthiame add-on therapy for epilepsy. Cochrane Database Syst Rev. 2015 Oct 28;(10):CD009472.