5-Ethynyl-2'-deoxyuridine (EdU) is a nucleoside analog of thymidine that is used to monitor de novo DNA synthesis through click chemistry.
CAS:61135-33-9
分子式:C11H12N2O5
分子量:252.2
纯度:98%
存储:Store at -20°C
Background:
5-Ethynyl-2’-deoxyuridine (EdU) is a nucleoside analog of thymidine that is used to monitor de novo DNA synthesis through click chemistry. Like 5-bromo-2’-deoxyuridine , EdU is incorporated into DNA during active DNA synthesis. It can then be detected using a fluorescent azide probe and copper catalysis using 1,3-dipolar cycloaddition. Modified nucleosides, including EdU, can be cytotoxic when added to cells for prolonged periods.