Nrf2-IN-1 (Compound 4f) 是 Nrf2 的抑制剂,具有作为治疗急性髓性白血病 (AML) 药物的前景。
CAS:1610022-76-8
分子式:C21H22ClN3O2
分子量:383.87
纯度:98%
存储:Store at -20°C
Background:
Nrf2-IN-1 (Compound 4f) is an inhibitor of nuclear factor-erythroid 2-related factor 2 (Nrf2), acts as a promising agent in acute myeloid leukemia (AML) therapy[1].
Nrf2[1]
[1]. Zhang J, et al. Discovery of a novel Nrf2 inhibitor that induces apoptosis of human acute myeloid leukemia cells. Oncotarget. 2017 Jan 31;8(5):7625-7636.