Vigabatrin盐酸盐(γ-Vinyl-GABA; Sabril)是GABA的结构类似物，能不可逆地抑制GABA氨基转移酶对GABA的分解代谢。
CAS：68506-86-5
分子式：C6H11NO2
分子量：129.16
纯度：98%
存储：Store at -20°C

Background:

Vigabatrin is a structural analog of the inhibitory neurotransmitter γ-aminobutyric acid (GABA) that irreversibly inhibits the catabolism of GABA by GABA transaminase.[1] It produces a dose-dependent increase in extracellular GABA, and has been shown to result in increasing seizure suppression.[2]

Reference:
[1]. Willmore, L.J., Abelson, M.B., Ben-Menachem, E., et al. Vigabatrin: 2008 Update. Epilepsia 50(2), 163-173 (2009).
[2]. Appleton, R.E. The new antiepileptic drugs. Arch. Dis. Child. 75(3), 256-262 (1996).