CCR1antagonist1是一种有效的CCR1拮抗剂,具有抗炎活性。
CAS:1010073-75-2
分子式:C22H22ClN7O2
分子量:451.91
纯度:98%
存储:Store at -20°C
Background:
CCR1 antagonist 1 is an antagonist of CCR1, with anti-inflammatory activity.
CCR1 antagonist 1 shows potent activities in the chemotaxis assay, with IC50< 100 nM[1].
In vivo, CCR1 antagonist 1 has in vivo anti-inflammatory activity and has superior pharmacokinetic properties[1].
[1]. Compounds for the treatment of osteoporosis and cancers. US 20100113472 A1