DGAT1-IN-1是高效DGAT1抑制剂,IC50值低于10nM(Hep3B细胞过表达DGAT1裂解物测得)。
CAS:1449779-49-0
分子式:C30H28F3N3O4
分子量:551.56
纯度:98%
存储:Store at -20°C
Background:
DGAT1-IN-1 is a potent DGAT1 inhibitor with IC50 of< 10 nM(cell lysate from Hep3B cells overexpressing human DGAT1).IC50 value:< 10 nMTarget: DGAT1 inhibitorImidazopyridine and imidazothiazole compounds as inhibitors of diacylglycerol o-acyltransferase type 1 enzyme and their preparationBy Kim, Dooseop; Bok, Juhan; Shin, Sunmi From PCT Int. Appl. (2013), WO 2013119040 A1 20130815.
[1]. Compounds as inhibitors of diacylglycerol o-acyltransferase type 1 enzyme , Patent: WO 2013119040 A1