F1063-0967是一种双特异性磷酸酶26(DUSP26)抑制剂，其IC50值为11.62μM。
CAS：613225-56-2
分子式：C24H24N2O5S2
分子量：484.59
纯度：98%
存储：Store at -20°C

Background:

F1063-0967 is a Dual-specificity phosphatase 26 (DUSP26) inhibitor with an IC50 of 11.62 μM.

F1063-0967 is a Dual-specificity phosphatase 26 (DUSP26) inhibitor with an IC50 of 11.62 μM. At concentration above 0.1 μM, F1063-0967 remarkably induces IMR32 cell apoptosis. F1063-0967 induces apoptosis in IMR-32 cell line with an IC50 value of 4.13 μM. F1063-0967 has no effect on HL7702 cell line, and little inhibition effect on SH-SY5Y cell line[1].

[1]. Ren JX, et al. Identification of novel dual-specificity phosphatase 26 inhibitors by a hybrid virtual screening approach based on pharmacophore and molecular docking. Biomed Pharmacother. 2017 May;89:376-385.