Topilutamide是一种局部非甾体类抗雄激素(NSAA)。
CAS:260980-89-0
分子式:C13H11F6N3O5
分子量:403.23
纯度:98%
存储:Store at -20°C
Background:
Topilutamide is a topical nonsteroidal antiandrogen (NSAA).
Prostate cancer is the most common cancer and one of the leading causes of cancer deaths in men. One of the commonly used approaches to treat metastatic prostate cancer is via first-generation nonsteroidal anti-androgens (NSAAs), namely Flutamide, Nilutamide, Bicalutamide and Topilutamide[1].
[1]. Suresh PS, et al. Review of HPLC and LC-MS/MS assays for the determination of various nonsteroidal anti-androgens used in the treatment of prostate cancer. Biomed Chromatogr. 2017 Jun 21.