large-conductance Ca2+-activated potassium channels activator
CAS：956014-19-0
分子式：C16H9BrF6N6S
分子量：511.24
纯度：98%
存储：Store at -20°C

Background:

NS 11021 is a potent and specific Ca2-activated big-conductance K＋ Channels (KCa1.1 channels) activator. NS 11021 at concentrations above 0.3 μM activates KCa1.1 in a concentration-dependent manner by parallelshifting the channel activation curves to more negative potentials[1].

参考文献:
[1]. Bentzen BH，et al. The small molecule NS11021 is a potent and specific activator of Ca2+-activated big-conductance K+ channels. Mol Pharmacol. 2007 Oct;72(4):1033-44.