生物活性
Acetaminophen (paracetamol) 是选择性环氧合酶-2 (COX-2) 的抑制剂，IC50 值为 25.8 μM。Acetaminophen 是一种有效的肝 N-乙酰转移酶 2 (NAT2) 抑制剂。它是广泛使用的解热和止痛药。
化学数据
| 目录号 | A10030 |
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 151.16 |
| Formula | C8H9NO2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 103-90-2 |
| Synonyms | Paracetamol |
| SMILES | CC(=O)NC1=CC=C(C=C1)O |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 66.16 mL | 330.78 mL | 661.55 mL |
| 0.5 mM | 13.23 mL | 66.16 mL | 132.31 mL |
| 1 mM | 6.62 mL | 33.08 mL | 66.16 mL |
| 5 mM | 1.32 mL | 6.62 mL | 13.23 mL |
*The above data is based on the productmolecular weight 151.16. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
