ElamipretideTFA(MTP-131TFA;RX-31TFA;SS-31TFA)是一种靶向作用于线粒体内膜的多肽,是心磷脂过氧化物酶(cardiolipinperoxidase)抑制剂。
CAS:1606994-55-1
分子式:C34H50F3N9O7
分子量:753.81
纯度:98%
存储:Store at -20°C
Background:
Elamipretide TFA (MTP-131 TFA; RX-31 TFA; SS-31 TFA) is a cardiolipin peroxidase inhibitor and mitochondria-targeting peptide[1].
Cardiolipin peroxidase[1]
[1]. Sabbah HN et al. Chronic Therapy With Elamipretide (MTP-131), a Novel Mitochondria-Targeting Peptide, Improves Left Ventricular and Mitochondrial Function in Dogs With Advanced Heart Failure. Circ Heart Fail. 2016 Feb;9(2):e002206.