Endoxan, Cytoxan, Neosar, Procytox, Revimmune, Cytophosphane
生物活性
Clafen (Cyclophosphamide)是氮芥芥烷化剂。烷基化剂将烷基（CnH2n+1）加至DNA。它在咪唑环的7个氮原子处将烷基连接到DNA的鸟嘌呤碱基。
化学数据
| 目录号 | A10224 |
| M. Wt | 261.1 |
| Formula | C7H15Cl2N2O2P |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 50-18-0 |
| Synonyms | Endoxan, Cytoxan, Neosar, Procytox, Revimmune, Cytophosphane |
| SMILES | C1CNP(=O)(OC1)N(CCCl)CCCl |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 38.3 mL | 191.5 mL | 383 mL |
| 0.5 mM | 7.66 mL | 38.3 mL | 76.6 mL |
| 1 mM | 3.83 mL | 19.15 mL | 38.3 mL |
| 5 mM | 0.77 mL | 3.83 mL | 7.66 mL |
*The above data is based on the productmolecular weight 261.1. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
