生物活性
Emtricitabine是一种用于治疗HIV感染的核苷逆转录酶抑制剂 (NRTI) 。
化学数据
| 目录号 | A10349 |
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 247.3 |
| Formula | C8H10FN3O3S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 143491-57-0 |
| Synonyms | Emtriva |
| SMILES | C1[C@H](O[C@H](S1)CO)N2C=C(C(=NC2=O)N)F |
溶解度
| In vitro | DMSO | 47 mg/mL (190.08 mM) |
| Water | 47 mg/mL (190.08 mM) |
| Ethanol | 9 mg/mL (36.4 mM) |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 40.44 mL | 202.18 mL | 404.37 mL |
| 0.5 mM | 8.09 mL | 40.44 mL | 80.87 mL |
| 1 mM | 4.04 mL | 20.22 mL | 40.44 mL |
| 5 mM | 0.81 mL | 4.04 mL | 8.09 mL |
*The above data is based on the productmolecular weight 247.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
