KDM4D-IN-1

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KDM4D-IN-1

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:	2098902-68-0
规格:	98%
分子量:	225.21

包装与价格：

包装	价格(元)
1mg	询价
5mg	询价
10mg	询价
50mg	询价
100mg	询价

KDM4D-IN-1是一种新型组蛋白赖氨酸去甲基化酶4D(KDM4D)抑制剂，IC50为0.41±0.03μM。
CAS：2098902-68-0
分子式：C11H7N5O
分子量：225.21
纯度：98%
存储：Store at -20°C

Background:

KDM4D-IN-1 is a new histone lysine demethylase 4D (KDM4D) inhibitor with an IC50 value of 0.41±0.03 μM.

KDM4D-IN-1 (Compound 10r) is the most potent one with an IC50 value of 0.41±0.03 μM against KDM4D. KDM4D-IN-1 displays almost no activity against KDM2B, KDM3B, and KDM5A (IC50>10 μM), indicating that KDM4D-IN-1 has a good selectivity for KDM4D against other selected KDMs[1].

[1]. Fang Z, et al. Discovery of pyrazolo[1,5-a]pyrimidine-3-carbonitrile derivatives as a new class of histone lysine demethylase 4D (KDM4D) inhibitors. Bioorg Med Chem Lett. 2017 Jul 15;27(14):3201-3204.