生物活性
Phenprocoumon是一种维生素K拮抗剂，可通过阻止凝血因子II，VII，IX和X的合成来抑制凝血。它用于预防和治疗血栓栓塞性疾病（血栓形成/肺栓塞）。
化学数据
| 目录号 | A10656 |
| M. Wt | 280.3 |
| Formula | C18H16O3? |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 435-97-2 |
| Synonyms | Marcoumar, Marcumar and Falithrom |
| SMILES | CCC(C1=CC=CC=C1)C2=C(C3=CC=CC=C3OC2=O)O |
溶解度
| In vitro | DMSO | 55 mg/mL (196.2 mM) |
| Water | Insoluble |
| Ethanol | 55 mg/mL (196.2 mM) |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 35.68 mL | 178.38 mL | 356.76 mL |
| 0.5 mM | 7.14 mL | 35.68 mL | 71.35 mL |
| 1 mM | 3.57 mL | 17.84 mL | 35.68 mL |
| 5 mM | 0.71 mL | 3.57 mL | 7.14 mL |
*The above data is based on the productmolecular weight 280.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
