生物活性
Phlorizin (Phloridzin)是SGLT1和SGLT2的竞争性抑制剂。
靶点信息
化学数据
| 目录号 | A10724 |
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 436.4 |
| Formula | C21H24O10 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 60-81-1 |
| Synonyms | Phlorhizin, Phlorizoside |
| SMILES | C1=CC(=CC=C1CCC(=O)C2=C(C=C(C=C2O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)O)O)O |
溶解度
| In vitro | DMSO | Warmed: 81 mg/mL (185.6 mM) |
| Water | Insoluble |
| Ethanol | Warmed: 8 mg/mL (18.33 mM) |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 22.91 mL | 114.57 mL | 229.15 mL |
| 0.5 mM | 4.58 mL | 22.91 mL | 45.83 mL |
| 1 mM | 2.29 mL | 11.46 mL | 22.91 mL |
| 5 mM | 0.46 mL | 2.29 mL | 4.58 mL |
*The above data is based on the productmolecular weight 436.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
