Mabuterol is an agonist of the β2-adrenergic receptor (β2-AR).
CAS：56341-08-3
分子式：C13H18ClF3N2O
分子量：310.7
纯度：98%
存储：Store at -20°C

Background:

Mabuterol is an agonist of the β2-adrenergic receptor (β2-AR). It induces relaxation of isolated tracheal muscle in guinea pigs and inhibits bronchoconstriction in a guinea pig model of experimental asthma. Administration of mabuterol decreases blood pressure and increases heart rate in a dose-dependent manner in rats, cats, and dogs. These effects are reversed by the selective β2-AR antagonist ICI 118551 , indicating mabuterol is acting at β2-ARs. At concentrations ≥1 μM, mabuterol acts as a β1-AR antagonist in isolated dog right atria.