Theaflavin是一种天然的甲型流感(H1N1)神经氨酸酶抑制剂。
CAS：4670-05-7
分子式：C29H24O12
分子量：564.49
纯度：98%
存储：Store at -20°C

Background:

Theaflavin is a suitable natural inhibitor against influenza A (H1N1) neuraminidase.

Theaflavin, found in green tea, is observed to inhibit H1N1 NA proteins strongly supported by lowest docking energy. Theaflavin is a plant product traditionally used for treatment of influenza infection. Green tea is particularly rich in polyphenolic compounds like Theaflavin. Theaflavin derivatives have shown pronounced antiviral activity. Theaflavin is found to interact with the amino acid residues like Arg118, Asp151, Asp 152, Arg193, Asp199, Asn344, and Arg430 of NA by forming hydrogen bonds[1].

[1]. Sahoo M, et al. Identification of Suitable Natural Inhibitor against Influenza A (H1N1) Neuraminidase Protein by Molecular Docking. Genomics Inform. 2016 Sep;14(3):96-103.