生物活性
Abacavir sulfate是一种核苷类似物逆转录酶抑制剂（NRTI）。
靶点信息
| HIV-1 reverse-transcriptase | | | | |
| | | | |
化学数据
| 目录号 | A11120 |
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 384.4 |
| Formula | C14H18N6O.H2SO4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 188062-50-2 |
| SMILES | C1CC1NC2=NC(=NC3=C2N=CN3[C@@H]4C[C@@H](C=C4)CO)N.OS(=O)(=O)O |
溶解度
| In vitro | DMSO | Insoluble |
| Water | 33 mg/mL (98.4 mM) |
| Ethanol | Insoluble |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 26.01 mL | 130.07 mL | 260.15 mL |
| 0.5 mM | 5.2 mL | 26.01 mL | 52.03 mL |
| 1 mM | 2.6 mL | 13.01 mL | 26.01 mL |
| 5 mM | 0.52 mL | 2.6 mL | 5.2 mL |
*The above data is based on the productmolecular weight 384.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
