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SCH 900776(MK-8776)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
SCH 900776(MK-8776)图片
CAS NO:891494-63-6
包装与价格:
包装价格(元)
5mg询价
10mg询价
50mg询价
100mg询价

SCH-900776, MK-8776, MK8776, MK 8776

生物活性

SCH 900776 (MK-8776)是靶向细胞周期检查点激酶1(Chk1)的药物,无细胞试验中IC50为3 nM,比作用于Chk2选择性高500倍。具有潜在的放射增敏和化学增敏活性。

化学数据

目录号A11167
作用机制Inhibitor (抑制剂)
M. Wt376.25
FormulaC15H18BrN7
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.891494-63-6
SynonymsSCH-900776, MK-8776, MK8776, MK 8776
SMILESNC1=C(Br)C([C@H]2CNCCC2)=NC3=C(C4=CN(C)N=C4)C=NN13

溶解度

In vitro (25°C)DMSO3 mg/mL (7.97 mM)
WaterInsoluble
EthanolInsoluble
In vivo4% DMSO+30% propylene glycol4 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM26.58 mL132.89 mL265.78 mL
0.5 mM5.32 mL26.58 mL53.16 mL
1 mM2.66 mL13.29 mL26.58 mL
5 mM0.53 mL2.66 mL5.32 mL

*The above data is based on the productmolecular weight 376.25. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

 
 
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