生物活性
Solifenacin succinate是毒蕈碱M3受体拮抗剂，用于治疗尿失禁。
靶点信息
化学数据
| 目录号 | A11215 |
| 作用机制 | Antagonist (拮抗剂) |
| M. Wt | 480.6 |
| Formula | C27H32N2O6 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 242478-38-2 |
| Synonyms | YM905, Vesicare |
| SMILES | C1CN2CCC1[C@H](C2)OC(=O)N3CCC4=CC=CC=C4[C@@H]3C5=CC=CC=C5.C(CC(=O)O)C(=O)O |
溶解度
| In vitro | DMSO | 3 mg/mL (6.24 mM) |
| Water | 85 mg/mL (176.88 mM) |
| Ethanol | 4 mg/mL (8.32 mM) |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 20.81 mL | 104.04 mL | 208.07 mL |
| 0.5 mM | 4.16 mL | 20.81 mL | 41.61 mL |
| 1 mM | 2.08 mL | 10.4 mL | 20.81 mL |
| 5 mM | 0.42 mL | 2.08 mL | 4.16 mL |
*The above data is based on the productmolecular weight 480.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
