N6-Ethyladenosine是一种腺苷衍生物,为腺苷受体(Adenosinereceptor)激动剂,对hA1AR和hA3AR的Ki值分别为4.9和4.7nM。
CAS:14357-08-5
分子式:C12H17N5O4
分子量:295.29
纯度:98%
存储:Store at -20°C
Background:
N6-Ethyladenosine is an adenosine derivative, acts as a Adenosine receptor agonist, with Kis of 4.9 and 4.7 nM for hA1AR and hA3AR, respectively[1].
Ki: 4.9 nM (hA1AR), 4.7 nM (hA3AR)[1]
N6-Ethyladenosine (Compound 28) exhibits more selectivity at hA1AR and hA3AR over hA2AR (Ki, 8900±770 nM)[1].
[1]. Kimand SK, et al. Three-dimensional quantitative structure-activity relationship of nucleosides acting at the A3 adenosine receptor: analysis of binding and relative efficacy. J Chem Inf Model. 2007 May-Jun;47(3):1225-33. Epub 2007 Mar 6.