生物活性
L-165,041是有效的PPARδ激动剂(Ki = 6 nM);与其他亚型相比,对小鼠和人类PPARδ受体的选择性显示> 100倍。
化学数据
目录号 | A11983 |
作用机制 | Agonist (激动剂) |
M. Wt | 402.44 |
Formula | C22H26O7 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for36 months. In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
CAS No. | 79558-09-1 |
Synonyms | L-165041, L165041 |
SMILES | CCCC1=C(C=CC(=C1O)C(=O)C)OCCCOC2=CC=C(C=C2)OCC(=O)O |
储备液配制
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
0.1 mM | 24.85 mL | 124.24 mL | 248.48 mL |
0.5 mM | 4.97 mL | 24.85 mL | 49.7 mL |
1 mM | 2.48 mL | 12.42 mL | 24.85 mL |
5 mM | 0.5 mL | 2.48 mL | 4.97 mL |
*The above data is based on the productmolecular weight 402.44. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.