LY345899人类胞质亚甲基四氢叶酸脱氢酶(DC301)的一个抑制剂,其Ki值为0.018μM。
CAS:10538-99-5
分子式:C20H21N7O7
分子量:471.42
纯度:98%
存储:Store at -20°C
Background:
LY 345899 is a human cytosolic methylenetetrahydrofolate dehydrogenase/cyclohydrolase (DC301) inhibitor, with a Ki of 0.018 μM.
[1]. Schmidt A, et al. Structures of three inhibitor complexes provide insight into the reaction mechanism of the human methylenetetrahydrofolate dehydrogenase/cyclohydrolase. Biochemistry. 2000 May 30;39(21):6325-35.