生物活性
Octreotide是sst2，sst3和sst5生长抑素受体的肽激动剂。克隆的人类生长抑素受体的IC50/Kd值（nM）为：290-1140（sst1），0.4-2.1（sst2），4.4-34.5（sst3），> 1000（sst4）和5.6-32（sst5）。
化学数据
| 目录号 | A12782 |
| 作用机制 | Antagonist (拮抗剂) |
| M. Wt | 1019.24 (free acid) |
| Formula | C49H66N10O10S2 . xC2H4O2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 79517-01-4 |
| SMILES | CC(C1C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCCN)CC2=CNC3=CC=CC=C32)CC4=CC=CC=C4)NC(=O)C(CC5=CC=CC=C5)N)C(=O)NC(CO)C(C)O)O.CC(=O)O |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 9.81 mL | 49.06 mL | 98.11 mL |
| 0.5 mM | 1.96 mL | 9.81 mL | 19.62 mL |
| 1 mM | 0.98 mL | 4.91 mL | 9.81 mL |
| 5 mM | 0.2 mL | 0.98 mL | 1.96 mL |
*The above data is based on the productmolecular weight 1019.24 (free acid). Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
