CC-90003是一种不可逆的,选择性的ERK1/2抑制剂,具有抗肿瘤活性。
CAS:1621999-82-3
分子式:C22H21F3N6O2
分子量:458.44
纯度:98%
存储:Store at -20°C
Background:
CC-90003 is an irreversible and selective inhibitor of ERK 1/2 with antitumor activity.
CC-90003 is an irreversible and selective inhibitor of ERK 1/2 with antitumor activity[1].
[1]. Monica M. Mita, et al. A phase Ia study of CC-90003, a selective extracellular signal-regulated kinase (ERK) inhibitor, in patients with relapsed or refractory BRAF or RAS-mutant tumors. Journal of Clinical Oncology 35, no. 15_suppl (May 20 2017) 2577-2577.