Quin-2AM是Ca2+的荧光螯合剂,对钙有很高的亲和性。
CAS:83104-85-2
分子式:C38H43N3O18
分子量:829.76
纯度:98%
存储:Store at -20°C
Background:
Quin-2AM is a fluorecent Ca2+ chelator, with high affinity for calcium.
Quin-2AM (20 µM) or A23187 (20 µM) drastically activate mTF activity without detectable effect on mTF synthesis; both of which show that sustained functional upregulation during 24 h culture does not enhance Marcks expression. Quin-2AM (20 µM) changes the non-detectable Marcks level in 24 h cultures[1].
[1]. Chu AJ, et al. Possible role of Marcks in the cellular modulation of monocytic tissue factor-initiated hypercoagulation. Br J Haematol. 2002 Aug;118(2):569-76.