MK-0736 is a novel potent and selective 11β-HSD-1 inhibitor. Emerging data from animal and human studies indicate an association of 11β-HSD1 over-expression with obesity and disorders in glucose and lipid metabolism. This has led to the hypothesis that selective inhibition of 11β-HSD1 could be used to treat MetS and diabetes 11beta-Hydroxysteroid dehydrogenase type 1 inhibitors are novel agents for the treatment of metabolic syndrome and obesity-related disorders.

纯度：≥98%

CAS：719272-79-4