Melarsonyl(Melarsonicacid)是一种驱虫剂,可有效抑制寄生虫(parasite)。
CAS:37526-80-0
分子式:C13H13AsN6O4S2
分子量:456.33
纯度:98%
存储:Store at -20°C
Background:
Melarsonyl (Melarsonic acid) is an anthelmintic agent which can inhibit parasite potently.
For acute infections produced by T. brucei brucei GVR, Potassium Melarsonyl exhibits trypanocidal activities. Potassium Melarsonyl (Trimelarsan) cures less than 50% mice at a dose of 25 μmol/kg for 4 consecutive days. At 60 μmol/kg, it cures all the mice in a chronic-infection model[1].
[1]. Loiseau PM, et al. Contribution of dithiol ligands to in vitro and in vivo trypanocidal activities of dithiaarsanes and investigation of ligand exchange in an aqueous solution. Antimicrob Agents Chemother. 2000 Nov;44(11):2954-61.