BTR-1是一种活性抗癌剂，能够诱导细胞周期S期停滞，影响DNA复制。BTR-1可激活凋亡(apoptosis)，导致细胞死亡。
CAS：18331-34-5
分子式：C12H11NOS2
分子量：249.35
纯度：98%
存储：Store at -20°C

Background:

BTR-1 is an active anti-cancer agent, causes S phase arrest, and affects DNA replication in leukemic cells. BTR-1 activates apoptosis and induces cell death[1]. Apoptosis[1]

BTR-1 (10, 50, 100, and 250 µM, 5 days) dose-dependently causes cytotoxicity in human leukemic cells, with IC50s of 8 and 6 µM at 48 and 72 h, respectively[1]. Cell Viability Assay[1] Cell Line: T-cell leukemic cell lines

[1]. Moorthy BT, et al. Novel rhodanine derivatives induce growth inhibition followed by apoptosis. Bioorg Med Chem Lett. 2010 Nov 1;20(21):6297-301.