Abiraterone metabolite 1 是 abiraterone 的 5β-还原代谢物。Abiraterone 是一种甾体药物,可抑制 CYP17A1,阻断雄激素的合成,延长前列腺癌的生存期。
CAS:1940176-03-3
分子式:C24H33NO
分子量:351.52
纯度:98%
存储:Store at -20°C
Background:
Abiraterone metabolite 1 is a 5β-reduced metabolite of abiraterone. Abiraterone, a steroidal drug, inhibits CYP17A1, blocks androgen synthesis and prolongs survival in prostate cancer.
[1]. Li Z, et al. Redirecting abiraterone metabolism to fine-tune prostate cancer anti-androgen therapy. Nature. 2016 May 26;533(7604):547-51.