3-Propylxanthine is a xanthine derivative that antagonizes adenosine receptors (Kis = 44, 32, and 6.3 μM for A1, A2A, and A2B, respectively) and cAMP phosphodiesterase (Ki = 42 μM).
CAS:41078-02-8
分子式:C8H10N4O2
分子量:194.2
纯度:98%
存储:Store at -20°C
Background:
3-Propylxanthine is a xanthine derivative that antagonizes adenosine receptors (Kis = 44, 32, and 6.3 µM for A1, A2A, and A2B, respectively) and cAMP phosphodiesterase (Ki = 42 µM). Through these actions, 3-propylxanthine induces smooth muscle relaxation, blocks smooth muscle contraction and VEGF secretion driven by adenosine receptor agonists, and reduces bronchial hyperresponsiveness.