Terlipressin是一个强的血管收缩剂,能通过小动脉的平滑肌细胞上受体V1,
CAS:14636-12-5
分子式:C52H74N16O15S2
分子量:1227.37
纯度:98%
存储:Store at -20°C
Background:
Terlipressin is a potent vasoconstrictor that acts via V1 receptors on arteriolar smooth muscle cells. Terlipressin can result in splanchnic vasoconstriction augmenting systemic arterial blood pressure with beneficial circulatory and renal effects that would be expected to also ameliorate the key pathophysiological changes responsible for the development of refractory ascites
[1]. Jao YT et al. Refractory torsade de pointes induced by terlipressin (Glypressin). Int J Cardiol, 2016 Jul 30, 222:135-140.