Diroximel fumarate (DRF) 是富马酸单乙酯 (MMF) 的前体药物,是一种控释制剂,可在体内迅速有效的转化为 MMF。
CAS:1577222-14-0
分子式:C11H13NO6
分子量:255.22
纯度:98%
存储:Store at -20°C
Background:
Diroximel fumarate (DRF) is a prodrug of monomethyl fumarate in a controlled-release formulation that rapidly and efficiently converts to MMF in the body[1].
[1]. Angela Wehr, et al. Relative Bioavailability of Monomethyl Fumarate after Administration of ALKS 8700 in Healthy Subjects (P1.403). Neurology. Apr 2018.